A putative integrase gene defines the distal end of a large cluster of ToxR-regulated colonization genes in Vibrio cholerae
Article Abstract:
The Vibrio cholera gene int, which encodes a protein related to the integrase family of site-specific recombinases, was identified. It is located to a site comprised of sequences that resemble bacteriophage attachment half-sites. It is apparently most closely related to the Escherichia coli cryptic prophage (CP4-57) integrase protein. Several V. cholerae strains were subjected to genomic analysis, showing that only vibrios that can cause epidemic Asiatic cholera have the TCP-ACF colonization gene cluster in association with the integrase.
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 1996
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Three new members of the serine-aspartate repeat protein multigene family of Staphylococcus aureus
Article Abstract:
The genes encoding the serine-aspartate (SD) repeat-containing proteins SdrC, SdrD and SdrE found in a Staphylococcus aureus strain Newman were examined. Previous studies revealed that the SD repeats were discovered in the S. aureus fibrinogen-clumping factors ClfA and ClfB. The Sdr proteins were distinguished from ClfA and ClfB by the two to five additional 110-113 residue repeated sequences found between region A and R-region. The C-terminal R-domains of the Sdr proteins possessed 132-170 SD residues.
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 1998
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A low-fibronectin-binding mutant of Staphylococcus aureus 879R4S has Tn918 inserted into its single fnb gene
Article Abstract:
A comparison of the structures of the fnb locus of strain 879R4SSp of Staphylococcus aureus and strain 8325-4 using PCR and Southern hybridization analysis showed that the former has a single fnb gene which is homologous to the fnbA gene. Sequencing of 41 bp of 5' non-coding and 237 bp of 5' coding DNA confirmed this finding. These showed that Tn918 was inserted 41 bp 5' to fnbA in the low-fibronectin-binding mutant 879R4SSp/1536, between the promoter and initiation codon.
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 1996
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- Abstracts: Cloning of the trkAH gene cluster and characterization of the Trk K+-uptake system of Vibrio alginolyticus
- Abstracts: Intraspecific genetic diversity of Oenococcus oeni as derived from DNA fingerprinting and sequence analyses. 16S-23S rDNA intergenic sequences indicate that Leuconostoc oenos is phylogenetically homogeneous
- Abstracts: Localization of denitrification genes on the chromosomal map of Pseudomonas aeruginosa. Protein C (OprC) of the outer membrane of Pseudomonas aeruginosa is a copper-regulated channel protein