Adaptive response of Schizosaccharomyces pombe to hydrogen peroxide and menadione
Article Abstract:
Pretreatment of Schizosaccharomyces pombe cells to sublethal concentrations of H2O2 and menadione (MD) induces resistance to oxidative stresses. The resistance is due to the induction of antioxidant enzymes. MD-induced resistance is greater than H2O2-induced resistance probably because MD increases the production of wider variety of enzymes. The GSH/GSSG ratio of the cells also increases. Cells in a stationary phase are more resistant than those in an exponential phase due to higher levels of the antioxidant enzymes.
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 1995
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Enzyme evolution in Rhodobacter sphaeroides: selection of a mutant expressing a new galactitol dehydrogenase and biochemical characterization of the enzyme
Article Abstract:
A functional mutant of Rhodobacter (R.) sphaeroides Si4 that can grow on galactitol, produces large quantities of a galactitol dehydrogenase (GDH). The N-terminal amino-acid sequence of the GDH reveals that it is a new enzyme as it exhibits properties different from other polyol dehydrogenases. Characterization of the enzyme indicates that it is a tetramer and though specific for AND (super +), catalyzes the oxidation of many sugar alcohols diols and secondary alcohols.
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 1995
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NAD(P)H:menadione oxidoreductase of the amitochondriate eukayote Giardia lamblia: a simpler homologue of the vertebrate enzyme
Article Abstract:
Results show that purified recombinant NAD(P)H:menadione oxidoreductase exhibits typical oxidoreductase activities with NADPH serving as its electron donor. Data also indicate that the enzyme possesses high amino acid sequence similarity to its vertebrate homologues.
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 2001
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