An expectation-maximization algorithm for the analysis of allelic expression imbalance
Article Abstract:
An expectation-maximization algorithm for analysis of allelic expression imbalance (AEI) providing a formal statistical framework is presented to test whether a candidate polymorphism is associated with allelic expression differences. It is observed that the cis-acting polymorphisms are important in determining interindividual differences in gene expression that lead to allelic expression imbalance.
Publication Name: American Journal of Human Genetics
Subject: Biological sciences
ISSN: 0002-9297
Year: 2006
User Contributions:
Comment about this article or add new information about this topic:
Elevated expression and genetic association links the SOCS3 gene to atopic dermatitis
Article Abstract:
A systematic analysis of global gene-expression patterns helped in finding that SOCS3 messenger RNA was significantly more highly expressed in skin from patients with atopic dermatitis. A genetic association was found between atopic dermatitis and a haplotype in the SOCS3 gene in two independent groups of patients.
Publication Name: American Journal of Human Genetics
Subject: Biological sciences
ISSN: 0002-9297
Year: 2006
User Contributions:
Comment about this article or add new information about this topic:
The genetics of congenital amusia (tone deafness): a family-aggregation study
Article Abstract:
An argument whether congenital amusia can be genetically transmitted is studied. It is concluded that congenital amusia is expressed by a deficit in processing musical pitch but not musical time and also show that the pitch disorder has a hereditary component.
Publication Name: American Journal of Human Genetics
Subject: Biological sciences
ISSN: 0002-9297
Year: 2007
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Human microsatellites applicable for analysis of genetic variation in apes and Old World monkeys. DNA fingerprinting in a butterfly, Bicyclus anynana (Satyridae)
- Abstracts: Distinguishing nitrous oxide production from nitrification and denitrification on the basis of isotopomer abundances
- Abstracts: Isolation of three dormancy QTLs as Mendelian factors in rice
- Abstracts: Determination of essential and variable residues in pediocin PA-1 by NNK scanning. Occurrence and antibiotic sensitivity of Listeria monocytogenes strains isolated from oysters, fish, and estuarine water
- Abstracts: Autoinducer 2 affects biofilm formation by Bacillus cereus. Swarming behavior of and hemolysin BL secretion by bacillus cereus