Bacterial disease in diverse hosts
Article Abstract:
The developement of new assays and technologies have allowed researchers to genetically manipulate the host to examine several hypotheses about virulence factor and host resistance mechanisms. Several studies on bacteria diseases were able to reveal that some pathogens can produce common virulence factors that cause disease in diverse hosts such as plants, animals and nematodes. One of these is the human pathogen Pseudomonas aeruginosa that was found to produce common virulence factors that cause disease in the plant Arabidopsis thaliana plant and in the nematode Caenorhabditis elegans.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1999
User Contributions:
Comment about this article or add new information about this topic:
Enteropathogenic E. coli (EPEC) transfers its receptor for intimate adherence into mammalian cells
Article Abstract:
The role of enteropathogenic E. coli (EPEC) receptor for outer membrane protein, Hp90, was established through PAGE-blotting of EPEC-infected HeLa cells. Results revealed that Hp90 was in fact, a bacterial protein (Tir). Its delivery to the host cell was mediated by the type III-secreted products EspA and EspB and then functions as the intimin receptor. A possible role of Tir tyrosine phosphorylation in intimin binding and pedestal formation was implicated.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1997
User Contributions:
Comment about this article or add new information about this topic:
Anti-immunology: Evasion of the host immune system by bacterial and viral pathogens
Article Abstract:
Some of the many molecular mechanisms that bacterial and viral and pathogens use to evade host immune defenses are highlighted. The success of each pathogen is directly dependant on its ability to mount effective anti-immune response within the infected host, which can ultimately result in acute disease, chronic infection or pathogen clearance.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2006
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Bacterial synergism or antagonism in a gel cassette system. Changes in bacterioplankton composition under different phytoplankton regimens
- Abstracts: Bacteriophage migration via nematode vectors: Host-parasite-consumer interactions in laboratory microcosms. Experimental examination of bacteriophage latent-period evolution as a response to bacterial availability
- Abstracts: Specific ribosomal DNA sequences from diverse environmental settings correlate with experimental contaminants
- Abstracts: Differential adsorption of occluded and nonoccluded insect-pathogenic viruses to soil-forming minerals. Fate of pathogens present in livestock wastes spread onto fescue plots
- Abstracts: Sex chromosome specialization and degeneration in mammals. A cell-surface receptor for lipocalin 24p3 selectively mediates apoptosis and iron uptake