Decision phase regulation of streptomycin production in Streptomyces griseus
Article Abstract:
The early part of the growth phase of Streptomyces griseus cells is the phase where the decision to produce streptomycin is made. S. griseus cells decide to produce or not to produce Sm during the early part of the vegetative or exponential growth phase (EGP), with the fixation of later production and differentiation possibly influenced by effector molecules only during this period. When the second EGP has begun, the commitment to produce Sm is irreversible, either by dilution into fresh medium or by effector molecules.
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 1996
User Contributions:
Comment about this article or add new information about this topic:
End-product control of enzymes of branched-chain amino acid biosynthesis in Streptomyces coelicolor
Article Abstract:
A variation in the specific activities of the enzymes acetohydroxy acid synthase and isopropylmalate synthase of branched-chain amino acid biosynthesis in Streptomyces coelicolor was observed under different physiological and genetic conditions. Similar effects on the specific activities of both enzymes were observed when the branched-chain amino acids leucine, isoleucine and valine were supplied singly or in combination in batch culture in minimal media.
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 1996
User Contributions:
Comment about this article or add new information about this topic:
Depression of streptomycin production by Streptomyces griseus at elevated growth temperature: studies using gene fusions
Article Abstract:
At temperatures higher than 37 degrees centigrade (C), the activity of streptomycin biosynthesis promoter PstrB1 decreases. However the StrR-independent expression of PstrB1 is unaffected by an increase in temperature. Thus the inability of Streptomyces griseus to produce streptomycin at temperature higher than 37 degrees C is probably due to a change in StrR activity at high temperatures.
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 1995
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Characterization and environmental regulation of outer membrane proteins in Xenorhabdus nematophilus. Purification and characterization of Xenorhabdicin, a phage tail-like bacteriocin, from the lysogenic strain F1 of Xenorhabdus nematophilus
- Abstracts: Timing and genetic regulation of commitment to sporulation in Bacillus subtilis. Medium-dependent sporulation resulting from a mutation in the spollAB gene of Bacillus subtilis
- Abstracts: Reduction of disulfide bonds by Streptomyces pactum during growth on chicken feathers. Characterization of a keratinolytic serine proteinase from Streptomyces pactum DSM 40530
- Abstracts: Regulation of chromosomal replication in E. coli: sequestration and beyond. E. coli SeqA protein binds oriC in two different methyl-modulated reactions appropriate to its roles in DNA replication initiation and origin sequestration
- Abstracts: Identification of domains conferring G protein regulation on inward rectifier potassium channels. Strong voltage-dependent inward rectification of inward rectifier K+ channels is caused by intracellular spermine