Differences in genetic diversity of nonencapsulated Haemophilus influenzae from various diseases
Article Abstract:
Multilocus enzyme electrophoresis was used in the analysis of 80 nonencapsulated Haemophilus influenzae isolates from patients with meningitis, otitis, chronic bronchitis and cystic fibrosis. Isolates were also recovered from healthy carriers. Genetic distribution of acute disease isolates was concluded as not random over the five electrophoretic types, although the genetic diversity within the groups was not different. The effect of bacterial persistence in the host on the genetic diversity of H. influenzae was also discussed.
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 1997
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An in silico evaluation of Tn916 as a tool for generalized mutagenesis in Haemophilus influenzae Rd
Article Abstract:
Haemophilus influenzae causes upper and lower respiratory tract infections. The entire genome sequence of H. influenzae Rd has recently been determined. The transposon Tn916 has been evaluated as a tool for generalized mutagenesis of the H. influenzae genome. 16 putative target sites were identified, and a new consensus sequence was derived using the observed nucleotide sequences. The curve-twist-curve DNA topology of the sequence is common to all Tn916 integration sites.
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 1998
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Phase variation of H. influenzae fimbriae: transcriptional control of two divergent genes through a variable combined promoter region
Article Abstract:
Phase variation in H. influenza fimbriae is governed at the transcriptional stage of two divergently oriented genes, the hifA (major fimbrial subunit) and the hifB (fimbrial chaperone subunit). The bidirectional regulation of hifA and hifB transcriptions originates from the clustering of the hifA and hifB promoter regions, and functions due to variations in the length of the repetitive sequence of TA units in the DNA backbone.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1993
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- Abstracts: Intraspecific genetic diversity of Oenococcus oeni as derived from DNA fingerprinting and sequence analyses. 16S-23S rDNA intergenic sequences indicate that Leuconostoc oenos is phylogenetically homogeneous
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