Distinct adhesive behaviors of neurons and neural precursor cells during regional differentiation in the mammalian forebrain
Article Abstract:
A study was conducted to determine whether cells from the three regions of the mammalian forebrian exhibit distinct cell adhesion and recognition properties that reflect their position, formation of subdivisions, neuronal differentiation and level of CAM expression. Using dissociation and reaggregation assays, cells from lateral regions exhibited the largest aggregates while cells from ventral region exhibited small aggregates. Cells from each region also expressed distinct levels of CAMs and other neuronal markers. It is only in the telencephalic region that CAM and neuronal differentiation are most prominent.
Publication Name: Developmental Biology
Subject: Biological sciences
ISSN: 0012-1606
Year: 1995
User Contributions:
Comment about this article or add new information about this topic:
Initial organization of neurons and tracts in the embryonic mouse fore- and midbrain
Article Abstract:
The mechanisms underlying neuronal patterning during development were investigated using lipophilic axon tracers to map neurons in the embryonic mouse fore- and midbrain. Tracts were organized orthogonally and two parallel longitudinal axon projections, one dorsal and the other ventral, were observed. It is suggested that the dorsal axon system subdivides the alar and basal plates along the entire neuraxis. The dorsal-ventral axons were not restricted to interneuromeric boundaries, as has been suggested in previous studies, but crossed the midline to the form the posterior and ventral tegmental commisures.
Publication Name: Developmental Biology
Subject: Biological sciences
ISSN: 0012-1606
Year: 1996
User Contributions:
Comment about this article or add new information about this topic:
Pattern formation in the developing mammalian forebrain: selective adhesion of early but not late postmitotic cortical and striatal neurons within forebrain reaggregate cultures
Article Abstract:
Researchers studied, in vitro, the function of cell adhesion in the alignment of like-birthdated neurons inside the rat telencephalon, and monitored the capacity of neurons of similar birthdates to relink with each other inside striatal or cortical reaggregates. Early postmitotic striatal and cortical neurons preferentially link with each other inside their related structures, but do not link in the case of late neurons. The alignment of cortical and striatal neuronal clusters may rely on a common adhesive process that crosses tissue-type boundaries.
Publication Name: Developmental Biology
Subject: Biological sciences
ISSN: 0012-1606
Year: 1993
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Fate of fumonisin B1 naturally contaminated corn during ethanol fermentation. Stabilization of pet operon plasmids and ethanol production in Escherichia coli strains lacking lactate dehydrogenase and pyruvate formate-lyase activities
- Abstracts: Postmeiotic transcription of X and Y chromosomal genes during spermatogenesis in the mouse. Conservation of mammalian secondary sperm receptor genes enables the promoter of the human gene to function in mouse oocytes
- Abstracts: Cloning and analysis of expression of a ubiquitin carboxyl terminal hydrolase expressed during oogenesis in Drosophila melanogaster
- Abstracts: Sources of calcium in sea urchin eggs during the fertilization response. The SpEGF III gene encodes a member of the fibropellins: EGF repeat-containingproteins that form the apical lamina of the sea urchin embryo
- Abstracts: Analysis of the tissue movements of embryonic wound healing: DiI studies in the limb bud stage mouse embryo. Cleavage asynchrony in the Tubifex embryo: involvement of cytoplasmic and nucleus-associated factors