Effects of partial inbreeding on fixation rates and variation of mutant genes

Article Abstract:

The fixation probabilities of single mutant genes in populations with partial inbreeding were investigated using diffusion methods. The critical parameters in the estimates are the coefficients of inbreeding due to nonrandommating, F, and the effective population size, N(sub e). The equations for F andN(sub e) were derived, and used to prove that the average time until extinctionof deleterious mutations is reduced by increasing F. The analyses suggest a great advantage of inbreeding in fixing advantageous mutants quickly. Inbreeding causes an increase in fixation probability, indicating an increase in the additive variance and in the asymptotic response to selection.

Analysis, Breeding, Inbreeding, Mutation breeding

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Effective size of nonrandom mating populations

Article Abstract:

A correction for the estimation of the variance effective size of mating populations is presented. The new calculations take into account an expected decrease in population size due to the possibility of nonrandom mating between related parents. The validity of the corrections was checked using stochastic simulation. An equation for use in cases where a specific number of full-sibling matings occurs every generation was also derived and validated.

Usage, Stochastic analysis, Population genetics

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On the effective size of populations with separate sexes, with particular reference to sex-linked genes

Article Abstract:

Two different methods are used for explaining the discrepancies in the equations related to the effective population size of flora and fauna with different sexes. The first method is based on the idea that sex of progeny is not capable of being detected. The second method includes techniques, which involve the identification of the sexes of offsprings and parents. The second method provides a better explanation than the first method.

Sex chromosomes

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