Germ-cell loss extends C. elegans life span through regulation of DAF-16 by kri-1 lipophilic-hormone signaling
Article Abstract:
Genes required for germline removal to extend life span are identified and analyzed. It is found that the reproductive system communicates with the intestine through lipophilic-hormone signaling and that a gene called kri-1 is likely to act in the intestine to promote DAF-16 nuclear localization in response to this signal.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2006
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The plasticity of aging: Insights from long-lived mutants
Article Abstract:
A description of the long-lived mutants and insights regarding the process of aging are presented. The results indicate that the delays in age-related diseases could be caused by the mutations that affect the longevity pathways.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2005
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Understanding the odd science of aging
Article Abstract:
The existing theories regarding the process of aging are reviewed. The study indicates that the process of aging can occur due to the failure of the living systems to stay alive and their struggle to keep going on.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2005
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