Hedgehog signaling in germ cell migration
Article Abstract:
Research has been conducted on the somatic gonad precursor cells and germ cells which originate at distant sites. Results indicate that the germ cells must undergo complex cell movements to reach somatic gonad precursor cells and that the hedgehog-dependent signal affect the germ cells directing their migration toward the source of hedgehog protein and is needed for the proper germ cell migration.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2001
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Signaling downstream to Eph receptors and ephrin ligands
Article Abstract:
The authors review publications on the Eph receptors and ephrin ligands in investigating molecular mechanisms of the cellular interactions which regulate axon guidance, cell migration and morphogenesis. The topics of interest include the mechanisms used by these receptors and ligands to control discrete steps in the development of the nervous system.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2001
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Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes
Article Abstract:
Research has been conducted on the beta cell sense glucose which stimulates insulin secretion. The role of the uncoupling protein-2 in regulating insulin secretion has been investigated and the results are reported.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2001
User Contributions:
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