Initial steps in the degradation of methoxychlor by the white rot fungus Phanerochaete chrysosporium
Article Abstract:
The mechanisms of dechlorination and hydroxylation reactions during methoxychlor degradation by Phanerochaete chrysosporium were analyzed to determine the characteristics of xenobiotic metabolism. The mineralization of [ring-14C]methoxychlor [1,1,1-trichloro-2,2-bis(4-methoxyphenyl)ethane] by the white rot fungus led to the formation of metabolites such as the 1-dechloro derivative of 1,1-dichloro-2,2-bis(4-methoxyphenyl)ethane and 2-hydroxy derivative of 2,2,2-trichloro-1,1-bis(4-methoxyphenyl)ethanol. Furthermore, the mineralization of methoxychlor also involves the benzylic hydroxylation of the pesticide.
Publication Name: Applied and Environmental Microbiology
Subject: Biological sciences
ISSN: 0099-2240
Year: 1997
User Contributions:
Comment about this article or add new information about this topic:
Fluorene oxidation in vivo by Phanerochaete chrysosporium and in vitro during manganese peroxidase-dependent lipid peroxidation
Article Abstract:
Experiments are performed to determine whether transformation of fluorene occurs during the lipid peroxdiation reactions mediated by Phanerochaete chrysosporium peroxidases. In vitro kinetics and intermediates are identified together with in vivo metabolite profiles. Results suggest that t the oxidation of fluorene in vitro is inhibited by the free radical scavenger butylated hydroxytoluene bu not by the lignin peroxidase inhibitor NaVO3.
Publication Name: Applied and Environmental Microbiology
Subject: Biological sciences
ISSN: 0099-2240
Year: 1996
User Contributions:
Comment about this article or add new information about this topic:
Polycyclic aromatic hydrocarbon-degrading capabilities of Phanerochaete laevis HHB-1625 and its extracellular ligninolytic enzymes
Article Abstract:
Experiments are performed to determine the the polycyclic aromatic hydrocarbon (PAH)-degrading capacity of Phanerochaete laevis HHB-1625 and its extracellular enzymes in the nitrogen-limited liquid and culture media. Results show that P. laevis is capable of extensive transformation of anthracene, phenanthrene, benzanthracene and benzopyrene. It also contains crude extracellular peroxidases which can transform a number of PAHs.
Publication Name: Applied and Environmental Microbiology
Subject: Biological sciences
ISSN: 0099-2240
Year: 1996
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Cloning of a cDNA encoding cellobiose dehydrogenase, a hemoflavoenzyme from Phanerochaete chrysosporium. Purification and characterization of a cellulose-binding beta-glucosidase from cellulose-degrading cultures of Phanerochaete chrysosporium
- Abstracts: Ether-bond scission in the biodegradation of alcohol ethoxylate nonionic surfactants by Pseudomonas sp. strain SC25A
- Abstracts: Molecular analysis of a laccase gene from the white rot fungus Pycnoporus cinnabarinus. The ligninolytic system of the white rot fungus Pycnoporus cinnabarinus: purification and characterization of the laccase
- Abstracts: Enzymes involved in anaerobic polyethylene glycol degradation by Pelobacter venetianus and Bacteroides strain PG1
- Abstracts: Site-specific phosphorylation of I(kappa)B(alpha) by a novel ubiquitination-dependent protein kinase activity