Evolutionary implications of the frequent horizontal transfer of mismatch repair genes

Article Abstract:

Phylogenetic analysis of bacterial mismatch repair (MMR) genes from Escherichia coli reveal high sequence mosaicism reflecting their origin in diverse phylogenetic lineages suggesting a horizontal gene transfer. Data indicate that MMRs facilitate evolutionary adaptation by modulating the mutational and recombination processes.

United States, Gene mutations, Gene mutation, Evolution (Biology), Evolution, Germplasm resources, Gene frequency

---

Translational misreading: a tRNA modification counteracts a +2 ribosomal frameshift

Article Abstract:

Genetic studies of the misreading of a GA repeat introduced into the Escherichia coli lacZ gene have shown that in the bacterium errors occur mainly by a +2 translational frameshift controlled by a tRNA change involving the GidA and MnmE proteins. GidA and MnmE seem to act in the same tRNA modification pathway, the absence of which is brings on the +2 translational frameshift.

Physiological aspects, Gene expression, Cytochemistry, Transfer RNA

---

Interspecies gene exchange in bacteria: the role of SOS and mismatch repair systems in evolution of species

Article Abstract:

A study of the mating between Escherichia coli and Salmonella typhimurium species reveals that the genetic barrier demarcating the two species is recombinational and arises due to divergence of genomic sequences. An SOS system regulates, while mismatch pair enzymes block the interspecies recombination that also activates a RecBC-dependent SOS response in female E. coli. The opposite functions of the SOS system and enzymes enable them to control the level of genetic isolation and the rate of accumulation of divergence.

DNA repair

Similar abstracts:

• Abstracts: A putative exchange factor for Rho1 GTPase is required for initiation of cytokinesis in Drosophila. Doing the MATH: Is the mouse a good model for fly development?
• Abstracts: Genetic architecture of fitness and nonfitness traits: empirical patterns and development of ideas. Balanced vs. slightly unbalanced selection
• Abstracts: A low G+C content genetic island in Mycobacterium avium subsp. paratuberculosis and M. avium subsp. silvaticum with homologous genes in Mycobacterium tuberculosis
• Abstracts: Culture change and stress in Western Samoan youth: methodological issues in the cross-cultural study of stress and immune function
• Abstracts: Drosophila p53 binds a damage response element at the reaper locus. p53: death star

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.