Isolation of canCHS1A, a variant gene of Candida albicans chitin synthase

Article Abstract:

The canCHS1A gene of the Candida albicans chitin synthase encodes a polypeptide constituting 775 amino acid residues. The polypeptide has one amino acid less than that encoded by the canCHS1 gene. The canCHS1A gene, a variant gene of the canCHS1, is functionally identical to the sacCHS2 in Saccharomyces cerevisiae. Polyoxin D and nikkomycin Z inactivates the canChs1A enzyme. The gene cloning and sequencing are described.

Genetic aspects, Enzymes, Cloning

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The Candida albicans gene for mRNA 5'-cap methyltransferase: identification of additional residues essential for catalysis

Article Abstract:

Research was conducted to examine the catalysis of the enzyme mediating RNA capping reaction in Candida albicans. The results indicate that amino acid residues like leucine, glycine, glutamic acid, and an unidentified acidic amino acid are involved in the catalysis.

Usage, Testing, RNA, Yeast, Yeast (Food product), Recombinant proteins, Catalysis, Amino acid sequence, Amino acid sequencing

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Reduced virulence of Candida albicans mutants lacking the GNA1 gene encoding glucosamine-6-phosphate acetyltransferase

Article Abstract:

Research has been conducted on Candida albicans GNA1 gene. The examination of C. albicans mutant's virulence in confirming the physiological importance of the yeast GNA1 gene is discussed.

Statistical Data Included, Phosphates, Gene expression, Virulence (Microbiology), Glucosamine, Microbiological research

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