Modulation of lipid metabolism and spiramycin biosynthesis in Streptomyces ambofaciens unstable mutants
Article Abstract:
The integration of a polyketide synthase (PKS) gene within the amplified unit DNA (AUD205) of Streptomyces ambofaciens has been found to alter the lipid metabolism rate of the strain. Experimental results revealed that all samples introduced with a mutant strain NSA205 strain manifested reduced ability to produce spiramycin. Majority of the strain further exhibited partial deletion of the AUD205 DNA. Environmental conditions and the physiological condition of bacteria have also been shown to influence the lipid composition of S. ambofaciens.
Publication Name: Applied and Environmental Microbiology
Subject: Biological sciences
ISSN: 0099-2240
Year: 1999
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Interaction of ruminal bacteria in the production and utilization of maltoologisaccharides from starch
Article Abstract:
The rate of starch degradation and the subsequent utilization of maltooligosaccharides during the growth of ruminal bacteria population was investigated. Pure cultures of amylolytic Streptococcus bovis, Butyrivibrio fibrisolvens, Bacteroides ruminicola and nonamylolytic Selenomonas ruminantium were anaerobically grown using starch as growth substrates. The products of starch hydrolysis were monitored and the rate of accumulation of oligosaccherides were determined.
Publication Name: Applied and Environmental Microbiology
Subject: Biological sciences
ISSN: 0099-2240
Year: 1992
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Identification of Streptococcus thermophilus CNRZ368 genes involved in defense against superoxide stress
Article Abstract:
Molecular analysis of ten menadione-sensitive mutants that were obtained from insertional mutagenesis was undertaken for identifying the genes of Streptococcus thermophilus CNRZ368 involved in oxidative stress defense. Higher sensitivity to superoxide stress could be caused by the inactivation of sufD and iscU genes and a critical role could be played by [Fe-S] cluster repair in the oxidative stress defense of anaerobic bacteria.
Publication Name: Applied and Environmental Microbiology
Subject: Biological sciences
ISSN: 0099-2240
Year: 2004
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