Trehalose is required for the acquisition of tolerance to a variety of stresses in the filamentous fungus Aspergillus nidulans
Article Abstract:
Trehalose, a nonreducing disaccharide found at nigh concentrations in the filamentous fungus Aspergillus nidulans conidia and rapidly degraded with induction of conidial germination, has been found to be required for acquisition of tolerance to various stresses in the fungus. It appears that trehalose 6-phosphate is a physiological inhibitor of hexokinase, but that the control is not essntial for proper glycolytic flux in a. nidulans. Also tpsA transcription is not induced in resonse to heat shock or in conidiation.
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 2001
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Role of trehalose in survival of Saccharomyces cerevisiae under osmotic stress
Article Abstract:
Trehalose, a nonreducing disaccharide, plays an important physiological function in several bacteria and fungi. Some commercial strains of the Saccharomyces cerevisiae yeast have trehalose levels higher than 10% of the cell dry weight. Those strains having high trehalose levels, also exhibit increased dehydration resistance. The roles of trehalose and glycerol in yest cell survival when subjected to osmotic stress have been investigated, and results suggest that intracellular trehalose concentration is related directly to survival.
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 1998
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Oxalic acid production by Aspergillus niger: an oxalate-non-producing mutant produces citric acid at pH 5 and in the presence of manganese
Article Abstract:
Oxalic acid production by Aspergillus niger is discussed. An mutant which does not produce oxalate and for which data is presented, produces citric acid if at pH 5 with manganese present. Activity of oxaloacetate acetylhydrolase (OAH), the enzyme thought to be responsible for oxalate formation in A. niger, correlated with oxalate production and external pH seemed to be the primary factor regulating oxalic acid production by A. niger.
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 1999
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