Phosphorylation of histone H3 is required for proper chromosome condensation and segregation
Article Abstract:
A study was conducted to analyze the role supported by H3 phosphorylation in vivo in chromosome condensation and segregation. The DuPont Biolistic PDS-1000/He Particle delivery system was utilized to transform starved vegetative cells. Results indicated the association of H3 serine 10 phosphorylation with chromosome condensation and segregation in vivo. Findings also showed that it is required for proper chromosome dynamics.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1999
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Histone lysine demethylases and their impact on epigenetics
Article Abstract:
Methylation marks on the lysine residues of histone proteins are thought to contribute to epigenetic phenomena in part because of their apparent irreversibility. However, it is argued that the reversibility of histone lysine methyl marks does not jeopardize their epigenetic status and it is suggested that not all histone lysine methylation residues are equally reversible.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2006
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