Promoter mutations of an essential gene for pollen development result in disease resistance in rice

Article Abstract:

Disease resistance and sexual reproductive development are separate processes, however, it is shown that Xa13, a recessive allele conferring disease resistance against bacterial blight plays a key role in both disease resistance and pollen development. The dominant allele Xa13 is needed for both bacterial growth and pollen development as promoter mutations in Xa13 cause downregulation of expression resulting in fully recessive Xa13 with resistance powers.

Diseases and pests, Rice blast disease, Hybrid rice, Plant immunology, Disease resistance (Plants)

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Vestibular defects in head-tilt mice result from mutations in Nox3, encoding an NADPH oxidase

Article Abstract:

The vestibular system of the inner ear is responsible for the perception of motion and gravity, key elements of the organ being octocoia, tiny particles in the utricle and the saccule. An allelic series of mutations at the octoconia-deficient head tilt (het) locus, affecting the gene for NADPH oxidase 3 (Nox3) is presented.

Evaluation, Gene mutations, Gene mutation, Genetic research, Vestibular diseases

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Abnormal development of the locus coeruleus in Ear2(Nr2f6)-deficient mice impairs the functionality of the forebrain clock and affects nociception

Article Abstract:

The abnormal development of the locus coeruleus in Ear2(Nr2f6)-deficient mice is investigated. The results indicate that the functionality of the forebrain clock is impaired and the nociception is also affected due to the abnormal development of the locus coeruleus in Ear2(Nr2f6)-deficient mice.

Circadian rhythms, Nociceptors

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