RNase-sensitive DNA modification(s) initiates S. pombe mating-type switching
Article Abstract:
An experiment to show that Schizosaccharomyces pombe (S. pombe) relies on RNase-sensitive modifications in the DNA that leads to mating-type switching is carried out. The results highlight that such imprints can become a guiding star for other cellular processes and mark the sites where the replication forks are stalled by damage to template DNA.
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2004
User Contributions:
Comment about this article or add new information about this topic:
Visualizing Mu transposition: Assembling the puzzle pieces
Article Abstract:
A study is carried out in which an electron microscopy-based 3D model of the protein-DNA complex responsible for Mu transposition is presented. Details show that this model not only ties together years of accumulated biochemical and structural data, but also gives interesting insight in the case of the classical DNA transposons.
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2005
User Contributions:
Comment about this article or add new information about this topic:
Two for the price of one: a bifunctional intron-encoded DNA endonuclease-RNA maturase
Article Abstract:
The dual role of homing endonucleases, a bifunctional intron is described. Homing endonucleases functioning, as maturases are intron specific and act as cofactors to bind their intron-containing precursor RNA to facilitate splicing. Masturases facilitates their integration to new sites din DNA.
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2003
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: A novel amino acid modification in sulfatases that is defective in multiple sulfatase deficiency. Molecular basis for multiple sulfatase deficiency and mechanism for formylglycine generation of the human formylglycine-generating enzyme
- Abstracts: Genetic differentiation and habitat preference of flowering-time variants within Gymnadenia conopsea. A multiyear estimate of the effective pollen donor pool for Albizia julibrissin
- Abstracts: Comparison of virulence gene profiles of Escherichia coli strains isolated from healthy and diarrheic swine. Identification of a novel Cryptosporidium genotype in pigs
- Abstracts: Identification of novel Cryptosporidium genotypes from avian hosts. Identification of novel Cryptosporidium genotypes from the Czech Republic
- Abstracts: Evaluation of a clostridium perfingers predictive model, developed under isothermal conditions in Broth, to predict growth in ground beef during cooling