Salivaricin A2 and the novel lantibiotic salivaricin B are encoded at adjacent loci on a 190-kilobase transmissible megaplasmid in the oral probiotic strain streptococcus salivarius K12
Article Abstract:
The characterization of commercial probiotic Streptococcus salivarius strain K12 which is the prototype of those Streptococcus salivarius strains that are the most strongly inhibitory in a standardized test of streptococcal bacteriocin production was reported. The genetic loci encoding 2,368-Da salivaricin (SalA2) and 2,740-Da salivaricin B (SboB) in strain K12, which was fully characterized, was found to be localized nearly adjacent sites on pSsal-K12, a 190-kb megaplasmid.
Publication Name: Applied and Environmental Microbiology
Subject: Biological sciences
ISSN: 0099-2240
Year: 2007
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Cloning of the gene encoding streptococcin A-FF22, a novel lantibiotic produced by Streptococcus pyogenes, and determination of its nucleotide sequence
Article Abstract:
The cloning and sequencing of the SA-FF22 structural gene (scnA) is described and its relationship to lantibiotics is discussed. Streptococcus pyogenes FF22 produces streptococcin A-FF22 (SA-FF220), a lantibiotic. 51-amino acid prepeptide is encoded by the nucleotide sequence of the SA-FF22 structural gene (scnA).
Publication Name: Applied and Environmental Microbiology
Subject: Biological sciences
ISSN: 0099-2240
Year: 1993
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Purification and characterization of streptin, a type A1 lantibiotic produced by Streptococcus pyogenes
Article Abstract:
Research has been conducted on Streptococcus pyogenes strains inhibiting the growth of all indicators in a streptococcal bacteriocin typing scheme. Results demonstrate that this inhibitory profile is caused by type A1 lantibiotic streptin.
Publication Name: Applied and Environmental Microbiology
Subject: Biological sciences
ISSN: 0099-2240
Year: 2003
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