Selection and recombination drive the evolution of MHC class II DRB diversity in ungulates
Article Abstract:
A comparative analysis of 15 different ungulates species is undertaken to estimate the population recombination rate and to quantify levels of selection. Signatures of strong positive selection were observed and individual residues experiencing selection that were congruent with those constituting the peptide binding region of the human DRB gene were identified and in each species it was seen that recombination rates were significantly different from zero on the basis of likelihood-permutation tests.
Publication Name: Heredity
Subject: Biological sciences
ISSN: 0018-067X
Year: 2006
User Contributions:
Comment about this article or add new information about this topic:
Spatial patterns of mitochondrial and nuclear gene pools in chamois (Rupicapra r. rupicapra) from the Eastern Alps
Article Abstract:
Spatial pattern analysis of the variability of mitochondrial DNA and biparentally inherited genes of 443 chamois from Eastern Alps indicate that 67.09% of the variance is distributed among the four mitochondrial phylogenetic groups, while partioning among regional samples within the populations and among individuals within samples are 8.04% and 24.86%, respectively.
Publication Name: Heredity
Subject: Biological sciences
ISSN: 0018-067X
Year: 2003
User Contributions:
Comment about this article or add new information about this topic:
Diversity and evolution of the Mhc-DRB1 gene in the two endemic lberian subspecies of Pyrenean chamois, Rupicapra pyrenaica
Article Abstract:
A study is conducted to estimate the major histocompatibility complex (MHC) variability of the two Rupicapra pyrenaica subspecies of the Iberian Peninsula. Analysis of the second exon of the DRB1 gene of the MHC region detected low levels of genetic diversity in the Iberian chamois.
Publication Name: Heredity
Subject: Biological sciences
ISSN: 0018-067X
Year: 2007
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Properties of Nisin Z and distribution of its gene, nisZ, in Lactococcus lactis. Improvement of solubility and stability of the antimicrobial peptide nisin by protein engineering
- Abstracts: Transduction, restriction and recombination patterns in Escherichia coli. Sequence comparisons
- Abstracts: Select your words carefully. Evidence for rare recombination at the gametophytic self-incompatibility locus. Diploid-dependent regulation of gene expression: a genetic cause of abnormal development in fish haploid embryos
- Abstracts: Reduction of experimental Salmonella and Campylobacter contamination of chicken skin by application of lytic bacteriophages
- Abstracts: Purification and characterization of microbial gellan lyase. Characterization and molecular cloning of a novel enzyme, inorganic polyphosphate/ATP-glucomannokinase, of Arthrobacter sp. strain KM