The overall pattern of cardiac contraction depends on a spatial gradient of myosin regulatory light chain phosphorylation

Article Abstract:

Results demonstrate that a spatial gradient of phosphorylated myosin light chain across the heart brings about torsion, which facilitates blood to wrung and get pumped out of the heart. Data indicate that cardiac contraction occurs due to inverse alteration of torsion and stretch activation response.

Heart, Heart contraction, Heart beat, Heart rate, Myosin

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The zipper model of translational control: a small upstream ORF is the switch that controls structural remodeling of an mRNA leader

Article Abstract:

Research has been conducted on internal ribosome entry site within mRNA leader. The authors suggest that the structure of this entry site is dynamic, and that this RNA structure can be regulated via translational control.

Canada, Genetic aspects, Cells (Biology), Genetic regulation, Genetic transcription, Transcription (Genetics), Cells, Ribosomes, Messenger RNA, Amino acids, Structure

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Endoplasmic reticulum stress activates cleavage of CREBH to induce a systematic inflammatory response

Article Abstract:

The delineation of the molecular mechanism governing stimulus-induced activation of CREBH is discussed. CREBH plays an important role in the activation of an acute inflammatory response.

Science & research, Michigan, Research, Membrane proteins, Caenorhabditis elegans, Proteolysis, Homeostasis, Properties

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