There must be 50 ways to rule the signal: the case of the Drosophila EGF receptor
Article Abstract:
The regulation of extracellular signals has been known to be mediated via the receptor tyrosine kinase (RTK) signaling pathways. The Drosophila epidermal growth factor (EGF) RTKs (Egfr), on the other hand, have been recognized to be involved in a wide variety of developmental processes. It has been proposed that the ability of Egfr to regulate a multitude of signals can be attributed to the presence of multiple Egfr ligands that activate the RTK in a tissue-specific manner.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1997
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Genetic and developmental analysis of polytene section 17 of the X chromosome of Drosophila melanogaster
Article Abstract:
Genetic and developmental analyses of the polytene section 17 of the X chromosome of Drosophila melanogaster were conducted to identify genes involved in the regulation of oogenesis andd embryogenesis. The analyses identified 10 new gene loci, six of which were important in embryogenesis and oogenesis. The total number of genes identified within the region was 17, 12 of which were expressed during oogenesis and embryogenesis.
Publication Name: Genetics
Subject: Biological sciences
ISSN: 0016-6731
Year: 1992
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Doublesex surprises
Article Abstract:
Studies in Drosophila suggest that sexual dimorphism in the genital disc is controlled by sex-specific signaling, from the A/P organizer, and subsequent autonomously controlled sex determination and differentiation. The genital disc handles this integration leading to production and interpretation of extracellular signals.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2001
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- Abstracts: An autoregulatory cascade of EGF receptor signaling patterns the Drosophila egg. A family of rhomboid-like genes: Drosophila rhomboid-1 and roughoid/rhomboid-2 cooperate to activate EGF receptor signaling
- Abstracts: Asymmetry in the assembly of the RNAi enzyme complex. RISC assembly defects in the Drosophila RNAi mutant armitage
- Abstracts: Clathrin coats - threads laid bare. Exploring the mode-of-action of bioactive compounds by chemical-genetic profiling in yeast