When specialized sites are important for synapsis and the distribution of crossovers
Article Abstract:
Specialized sites in C. elegans and D. melanogaster have a significant role in meiotic recombination. The initiation of synapsis in organisms with specialized sites and those without are compared and it is proposed that early in prophase, synapsis needs an initiator, stimulated by crossover sites, to overcome inhibitory factors preventing synaptonemal complex (SC) formation between nonhomologous sequences.
Publication Name: BioEssays
Subject: Biological sciences
ISSN: 0265-9247
Year: 2007
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Endogenous inhibitors of RNA interference in Caenorhabditis elegans
Article Abstract:
The identification of two worm proteins namely RRF-3(1,2) and ERI-1(3) that can inhibit RNAi responses is emerged through the experiments designed to unravel RNAi mechanisms in Caenorhabditis elegans. The remarkable potency of RNAi in invertebrates is partly due to the molecular dissection of each molecule of long double-stranded RNA (dsRNA) into many species of short interfering RNAs (siRNAs).
Publication Name: BioEssays
Subject: Biological sciences
ISSN: 0265-9247
Year: 2004
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Endomesoderm specification in Caenorhabditis elegans and other nematodes
Article Abstract:
The molecular evolution of the endomesoderm gene regulatory network (GRN) of Caenorhabditis-elegans (C. elegans) is examined. It is concluded that the C. elegans endomesoderm GRN consist of a relatively small number of factors organized into a hierarchy that links together maternal gene products, blastomere specification genes, tissue/organ identity genes and differentiation genes.
Publication Name: BioEssays
Subject: Biological sciences
ISSN: 0265-9247
Year: 2006
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