Zebrafish: a new model on the pharmaceutical catwalk

Article Abstract:

This article illustrates the usefulness of zebrafish as a model organism for pharamacological research. Research shows that results from zeebrafish are comparable to those from mammalian systems with respect to cardiovascular, anti-angiogenic and anti-cancer drugs. Zeebrafish can be employed for screenings of chemical libraries, mode-of-action studies, analysis of gene function, toxicology and toxicogenomics among others.

Commercial Fishing, Fishing, Models, Fishes, Pharmaceutical research

---

Starting the protein synthesis machine: eukaryotic translation initiation

Article Abstract:

Research findings suggest that translation initiation is a dynamic process in which the 3'end of the mRNA plays a critical in the process. The initiation process lies between the transcriptome and the proteome in the gene expression pathway and involves several sequential protein-RNA and protein-protein interactions.

Australia, Physiological aspects, Protein synthesis, Gene expression, Protein biosynthesis, Messenger RNA, Genetic translation, Translation (Genetics)

---

Replacing animal experiments: Choices, chances and challenges

Article Abstract:

The origins and applications of some successful replacement methods used in fundamental medical research and in regulatory testing are reviewed. Focus is laid on three areas of research namely respiratory illnesses, pain and sepsis.

United States, Science & research, Research, Usage, Sepsis, Respiration disorders

Similar abstracts:

• Abstracts: Use of flow cytometry to follow the physiological states of microorganisms in cider fermentation processes. Killer toxin of Kluyveromyces phaffii DBVPG 6076 as a biopreservative agent to control apiculate wine yeasts
• Abstracts: The vertebrate limb: a model system to study the HOX/HOM gene network during development and evolution. Origin and evolution of the vertebrate vomeronasal system viewed through system-specific genes
• Abstracts: Mercury methylation and demethylation in anoxic lake sediments and by strictly anaerobic bacteria. Complete mineralization of benzene by aquifer microorganisms under strictly anaerobic conditions
• Abstracts: A new operation for producing disease-suppressive compost from grass clippings. Relationships among non-Acremonium sp. fungal endophytes in five grass species
• Abstracts: Proteins homologous to the Xenopus germ cell-specific RNA-binding proteins p54/p56 are temporally expressed in mouse male germ cells

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.