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A human hepatocyte factory

Article Abstract:

A new mouse model is developed that have helped in the expansion of human hepatocytes in vivo. This model has a large impact in the pharmaceutical industry as it is useful for drug-toxicity screening and the development of drugs against chronic hepatitis B and C virus.

Author: Shafritz, David A.

Publisher: Nature Publishing Co.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2007

Methods, Usage, Animal experimentation, Toxicity testing, Toxicity tests

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Microscale culture of human liver cells for drug development

Article Abstract:

A microtechnology-based process that uses elastomeric stencils to culture human liver cells in industry-standard multiwell format is described.

Author: Khetani, Salman R., Bhatia, Sangeeta N.

Publisher: Nature Publishing Co.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2008

Analysis, Gene expression, Microtechnology

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Subjects list: Research, Liver cells, Hepatocytes

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