An integrated mass spectrometric and computational framework for the analysis of protein interaction networks
Article Abstract:
A novel strategy, called the MasterMap system, is described for analyzing protein complexes through the integration of label-free, quantitative mass spectrometry and computational analysis. The MasterMap system has improved the specificity and sensitivity of interaction networks, assessed the post-translational modification and provided dynamic interaction profiles in order to overcome the limitations of the current methods for protein complexes.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2007
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A high quality catalog of the Drosophila melanogaster proteome
Article Abstract:
The predicted Drosophila melanogaster proteome was cataloged by detecting 9,124 proteins form 498, 00 redundant and 72,281 distinct peptide identification. It is shown that the high-quality proteomics data provides crucial information to amend genome annotation and to confirm many predicted gene models.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2007
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The functional genomics experiment model (FuGE): an extensible framework for standards in functional genomics
Article Abstract:
The Functional Genomics Experimental data model (FuGE) is developed for facilitating the convergence of data standards for comprehensive analyses in biology. The use of FuGE in functional genomics workflows enables transparent data management and mining.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2007
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