Gene targeting using zinc finger nucleases
Article Abstract:
Zinc finger nucleases (ZFNs) improve the efficiency of gene targeting by introducing deoxyribonucleic acid (DNA) double-strand breaks in target genes, which then stimulate the cell's endogenous homologous recombination machinery. Test results show that ZFNs can be used to create targeting frequencies of up to 20% in a human disease-causing gene.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2005
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The small world of metabolism
Article Abstract:
Many organisms that are now being sequenced have not had their biochemistry studied, such is the pace of genome sequencing.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2000
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Electrochemical DNA analysis comes of age
Article Abstract:
High-density, high-throughput microarray systems may replace fluorescence as the dominant method for DNA analysis.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2000
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