HDAC inhibitors overcome first hurdle
Article Abstract:
The first histone deacetylase (HDAC) inhibitor has overcome the first hurdle as it has got the approval by the U.S. Food and Drug Administration (FDA) in October 2006. The development of Zolinza, from Merck in Whitehouse Station, New Jersey, for treating a rare cancer, cutaneous T-cell lymphoma is kept very low, as there is an aggressive development by industry and the National Cancer Institute to bring HDAC inhibitors to market for every major tumor type.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2007
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New apoptosis drugs face critical test
Article Abstract:
Surging numbers of therapeutic proteins and small molecules, rationally designed to trigger cell death, are entering the clinic against cancer. Apoptosis is absolutely necessary for human development and survival, with millions of cells committing suicide daily as a way to prevent uncontrolled growth.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2005
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