Quantitative proteomics?
Article Abstract:
cDNAs which are short oligonucleotides, arrayed on chips have become powerful tools to probe cellular mRNA populations. They allow the comprehensive determination of the expression of individual genes in a given cell type or cell state, the so-called "transcriptome". Although such analyses afford significant information, it would be equally useful to measure individual protein levels directly by proteomic analysis.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 1999
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From genomics to proteomics
Article Abstract:
The study of proteomics described as a set of proteins encoded by genome evokes the set of all proteins isoforms and modifications, the interactions between them, and the structural description of proteins. Technological improvements and organization of international proteomics projects is required to fulfill the potential of proteomics.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2003
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Temporal analysis of phosphotyrosine-dependent signaling networks by quantitative proteomics
Article Abstract:
The study of global dynamics of phosphotyrosine-based signaling events in early growth factor stimulation is detailed. The proteomes of three cell populations are metabolically encoded with different stable isotopic forms of arginine.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2004
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