The sweet side of biomarker discovery
Article Abstract:
The involvement of glycans in tumor progression can be used to diagnose, predict susceptibility and monitor cancer progression. Biomolecules can complement DNA and protein for early diagnosis of cancer with development of appropriate technologies for clinical translation but owing to its low detection limits, efficiency and rapid characterization capabilities, mass spectrometry remains popular technique for biomarker discovery.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2006
User Contributions:
Comment about this article or add new information about this topic:
The role of companion diagnostics in the development and use of mutation-targeted cancer therapies
Article Abstract:
Genetic differences distinguish cancer cells from normal cells and hence therapeutic advances are based on agents that specifically target the products of the genes that are mutated in cancer cells. Companion diagnostic tests that would help to identify patients who are most likely to benefit from these therapies and simplify the drug discovery process are described.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2006
User Contributions:
Comment about this article or add new information about this topic:
Genetic profiteering
Article Abstract:
Clinical genetics and genetic tests are fast developing into commodities which consumers can order to find out information such as their ancestry and cancer risk. The reaction to such a development is mixed, with backers of the endeavor arguing that people have a right for such information and critics viewing them as potentially dangerous and exploitative.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2006
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Exploring the role of culture in trust development with service providers. Business (not) as usual: crisis management, service recovery and the vulnerability of organisations
- Abstracts: The impact of managing director changes and financial distress on audit qualification and auditor switching. The 'Independence' of expert opinions in corporate takeovers: agreeing with directors' recommendations
- Abstracts: The World Wide Web as an industrial marketing communication tool: models for the identification and assessment of opportunities
- Abstracts: The effect of keyboard keyswitch make force on applied force and finger flexor muscle activity. An evaluation of the ergonomics of three computer keyboards
- Abstracts: The next generation? The emerging nanomedicine landscape. Trendspotting: Betting strong but playing safe