Structural flexibility of the d(CCAGTACTGG)(sub 2) B-DNA decamer and its complex with two polyamides
Article Abstract:
Molecular dynamics simulations of the d(CCAGTACTGG)(sub 2) B-DNA decamer alone and complexed with two polyamide ligands exhibit a distinct structural flexibility of the DNA. The DNA double helices are curved in the simulation constrating the x-ray determined structures.
Publication Name: Journal of Physical Chemistry B
Subject: Chemicals, plastics and rubber industries
ISSN: 1520-6106
Year: 2001
User Contributions:
Comment about this article or add new information about this topic:
Dynamics of DNA: BI and BII phosphate backbone transitions
Article Abstract:
It has been studied that the relaxation from BII state is much faster with high rate constants and depending on temperature. The structures of the B1 DNA seem similar to the x-ray crystallography than the all BII state.
Publication Name: Journal of Physical Chemistry B
Subject: Chemicals, plastics and rubber industries
ISSN: 1520-6106
Year: 2004
User Contributions:
Comment about this article or add new information about this topic: