Defects can increase the melting temperature of DNA-nanoparticles assemblies
Article Abstract:
DNA-gold nanoparticle assemblies can be used as an alternative technology to DNA microarrays for DNA detection and RNA profiling. The results have demonstrated that the surface-bound DNA display hybridization behavior different from that of free DNA, indicating that a detailed understanding of DNA-nanoparticle assembly phase behavior is required for quantitative interpretation of DNA-nanoparticle aggregation.
Publication Name: Journal of Physical Chemistry B
Subject: Chemicals, plastics and rubber industries
ISSN: 1520-6106
Year: 2006
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"One-into-many" model: An approach on DFT based reactivity descriptor to predict the regioselectivity of large systems
Article Abstract:
A model is developed to predict the regioselectivity of large chemical and biological systems. A large system, right-handed B-DNA is broken into small fragments in this model and then the local reactivity of the concerned atomic sites in the individual fragments are evaluated on the basis of DFT.
Publication Name: Journal of Physical Chemistry B
Subject: Chemicals, plastics and rubber industries
ISSN: 1520-6106
Year: 2007
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