Study of adsorption and penetration of E2(279-298) peptide into Langmuir phospholipid monolayers

Article Abstract:

A method to synthesize peptide corresponding to the sequence (279-298) of the Hepatitis G virus (HGV/GBV-C) E2 protein and surface activity measurements, pi-A compression isotherms, and penetration of E2 (279-298) into phospholipid monolayers spread at the air-water interface on the water and phosphate buffer subphases is presented. The observations show that the lipid acyl chain length is a significant factor to be considered in the study of peptide-lipid interactions.

Phosphates, Adsorption, Chemical synthesis

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Conductance of [alpha]-helical peptides trapped within molecular junctions

Article Abstract:

The investigation of mediated electron transfer was carried out by employing self-assembled monolayers of [alpha]-helical peptides on a gold surface. Measurements performed with peptides containing different numbers of amino acid residues indicate that the distance dependence of electron transmission through an [alpha]-helix is weaker than that through simple n-alkyl bridges.

Usage, Electron transport, Monomolecular films, Scanning tunneling microscopy

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Influence of the saturation chain and head group charge of phospholipids in the interaction of hepatitis G virus synthetic peptides

Article Abstract:

The properties at the air/water interface and the interaction of the hepatitis G virus synthetic peptide E1 and its palmitoyl with membrane phospholipids are studied using the Langmuir technique. The interaction is found to be influenced by the saturation of the acyl chain.

Peptide synthesis, Thin films, Multilayered, Multilayered thin films, Properties

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