Fluoroquinolones for the treatment of nongonococcal urethritis/cervicitis
Article Abstract:
Urethritis (inflammation of the lower urinary tract) caused by bacteria other than Neisseria gonorrhea occurs more frequently than that caused by Neisseria gonorrhea. Nongonococcal urethritis is usually caused by Chlamydia trachomatis, but it can also be caused by Ureaplasma urealyticum and various species of Mycoplasma, including Mycoplasma hominis. Genital infections caused by C. trachomatis are difficult to diagnose partly because chlamydial infections often do not cause any symptoms. The incidence of sickness is due to unidentified and untreated C. trachomatis infections is increasing. The Centers for Disease Control recommends that the sexual partners of all individuals diagnosed with nongonococcal urethritis, nongonococcal cervicitis and gonorrhea be treated with antibiotics that will kill chlamydia. The antibiotic tetracycline has been recommended for these cases. However, tetracycline is not very effective against U. urealyticum and Mycoplasma species. Therefore, it is suggested that the fluoroquinolones be used to treat patients with nongonococcal urethritis and nongonococcal cervicitis and their sexual partners. The fluoroquinolones, especially temafloxacin, are very effective against many types of bacteria, including U. urealyticum and Mycoplasma species. (Consumer Summary produced by Reliance Medical Information, Inc.)
Publication Name: American Journal of Medicine
Subject: Health care industry
ISSN: 0002-9343
Year: 1991
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Recent developments in the treatment of sexually transmitted diseases
Article Abstract:
At present, no single drug can effectively treat all types of sexually transmitted diseases (STD). Many types of bacteria can cause sexually transmitted diseases, including Chlamydia trachomatis (the most common STD pathogen), Neisseria gonorrhoea, Ureaplasma urealyticum, Mycoplasma hominis and Bacteroides fragilis. Strains of Neisseria gonorrhoea have evolved that are not killed by penicillin, that is, they are resistant to the effects of penicillin. The possible use of fluoroquinolones, including the recently developed fluoroquinolone temafloxacin, in the treatment of STDs is discussed. These agents, especially temafloxacin, have strong antimicrobial activity against a wide range of bacteria and are well tolerated by the body. They are found in high levels in the urine, which contributes to their effectiveness in treating STD pathogens in the urinary tract. (Consumer Summary produced by Reliance Medical Information, Inc.)
Publication Name: American Journal of Medicine
Subject: Health care industry
ISSN: 0002-9343
Year: 1991
User Contributions:
Comment about this article or add new information about this topic:
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