Rectal misoprostol versus intravenous oxytocin for the prevention of postpartum hemorrhage after vaginal delivery
Article Abstract:
A rectal suppository containing misoprostol was less effective than intravenous oxytocin in preventing postpartum hemorrhage in a study of 325 women. Oral misoprostol may be preferable, since it is cheap, easy to take, and can be stored at room temperature.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2001
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A comparison of misoprostol and prostaglandin E2 gel for preinduction cervical ripening and labor induction
Article Abstract:
The drug misoprostol may be effective at ripening the cervix in preparation for induction of labor, but the dosage is in question. Researchers compared the effectiveness of vaginally administered misoprostol (prostaglandin E1) to that of dinoprostone (prostaglandin E2) gel applied to the cervix for cervical ripening before induction of labor. More patients receiving misoprostol required oxytocin to induce labor less often, had riper cervices before induction of labor, and were able to deliver vaginally within 24 hours of induction. Undesirable side effects of misoprostol were a rapid rate of uterine contractions and meconium in the amniotic fluid. The dosage of misoprostol was 50 microgram tablets every three hours for up to six doses.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1995
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A comparison of intermittent vaginal administration of misoprostol with continuous dinoprostone for cervical ripening and labor induction
Article Abstract:
A medicated tablet called Cytotec that contains misoprostol and is placed on the cervix appears to be equally effective in reducing a woman's time in labor as a medicated, time-released vaginal suppository called Cervidil that contains dinoprostone. Ninety-nine women were treated with Cytotec and 101 women were treated with Cervidil to induce labor. Women given Cytotec delivered an average of one hour earlier and were less likely to experience rapid contractions but were slightly more likely to need oxytocin than those given Cervidil. An equal number of women in each group ultimately delivered by cesarean.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1997
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- Abstracts: Mifepristone versus vaginally administered misoprostol for cervical priming before first-trimester termination of pregnancy: a randomized, controlled study
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