A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less

Article Abstract:

A protease inhibitor combined with two nucleoside analogs seems to be more effective than the nucleoside analogs alone in preventing the progression of HIV infection. These are all drugs used to treat HIV infection. A total of 1,156 HIV-infected patients were randomly assigned to take the nucleoside analogs zidovudine and lamivudine alone or combined with the protease inhibitor indinavir. The group taking all three drugs had half the risk of progressing to AIDS or dying compared to those taking the nucleoside analogs. They also experienced greater increases in their CD4 cell counts and greater decreases in HIV RNA levels.

Evaluation, Product/Service Evaluation, Protease inhibitors, Zidovudine, Lamivudine, Indinavir (Medication)

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Management of newly diagnosed HIV infection

Article Abstract:

A case study of a 25-year-old previously healthy woman who was found to have a positive test for human immunodeficiency virus type 1 (HIV-1) antibody is presented. Experts suggest that patients with newly diagnosed HIV infection, the initial emphasis should be on counseling with regard to the disease process, limiting the risk of secondary transmission.

New England States, Women, Women's health, New England, Health counseling, Health counselling

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Patents versus patients? Antiretroviral therapy in India

Article Abstract:

The President of India issued a patent-amendment ordinance requiring 20-year patents on all new medications, which came into effect from January 1, 2005. Advocacy groups aroused many objections around the world for patients with human immunodeficiency virus (HIV) infection, who differentiated the proposed law as pitting patents against patients.

United States, India, Health aspects, Antiviral agents, Antiretroviral agents

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