A protective gene for graft-versus-host disease
Article Abstract:
A gene variation that produces high amounts of interleukin-10 may protect some stem cell transplant recipients from developing a serious complication of transplantation called graft-versus-host disease (GVHD). Interleukin-10 suppresses the immune response and helps the immune system tolerate the transplant. A 2003 study confirmed this effect in patients who received an HLA-identical transplant from a relative. Further research is needed to determine if it can occur between unrelated donors and recipients.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2003
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Sick chaperones, cellular stress, and disease
Article Abstract:
Systems of proteins known as molecular chaperones help to preserve a total set of functionally efficient proteins in cells during injury or anxiety. A study describes the contribution of defective chaperones to aging and many other diseases.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2005
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