Abnormal myocardial phosphorus-31 nuclear magnetic resonance spectroscopy in women with chest pain but normal coronary angiograms
Article Abstract:
Women who have chest pain but no evidence of coronary artery disease may still have ischemia. Ischemia is a decrease in the blood supply to an organ, in this case, the heart. Researchers used NMR spectroscopy to measure the ratio of phosphocreatine to ATP in 35 women with chest pain but no coronary artery disease and 12 healthy volunteers. This ratio is abnormal during periods of ischemia. Twenty percent of the women with chest pain had a lower ratio during a handgrip exercise than the healthy women.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2000
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Chest pain in women with normal coronary angiograms
Article Abstract:
Researchers need to determine if a change in the ratio of phosphocreatine to ATP is accompanied by evidence of heart dysfunction. A decrease in the ratio indicates an abnormal physiological response to stress in the small blood vessels of the heart. A study published in 2000 found that women with chest pain but no evidence of coronary artery disease were likely to develop an abnormal ratio when exercising. This could explain why they have chest pain, which is often caused by decreased blood flow to the heart.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2000
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Relationship of physical fitness vs body mass index with coronary artery disease and cardiovascular events in women
Article Abstract:
The relationships of measures of obesity and physical fitness with coronary artery disease (CAD) risk factors, angiographic CAD and adverse cardiovascular (CV) events in women evaluated for suspected myocardial ischemia are investigated. Women undergoing coronary angiography for suspected ischemia were found to have higher self-reported physical fitness scores independently associated with fewer CAD risk factors, less angiographic CAD and lower risk for adverse CV events.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2004
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