Acute reactions to drugs of abuse

Article Abstract:

There is new information on some toxic reactions to drugs of abuse. There are many ways to take cocaine that can cause a prompt, very brief toxic episode. Cocaine constricts the arteries of the heart and can cause seizures, strokes, and heart attacks. Treatment is limited to controlling excess body heat, irregular heart beat, and high blood pressure. Amphetamine toxicity is similar but lasts longer. Ammonium chloride can acidify the urine to help eliminate the drug. Opioids, such as heroin, may cause excessive damage to the heart and lungs. Naloxone will reverse most symptoms of opioid overdosing. Clonidine alleviates often severe withdrawal from opioids. The treatment of reactions to sedative-hypnotics, volatile inhalants, phencyclidine (PCP), hallucinogens, marijuana, anabolic steroids, and contaminants in impure drugs is discussed.

Drugs, Complications and side effects, Physiological aspects, Drug abuse, Narcotics, Overdose, Adverse drug reactions, Toxicological emergencies

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Drugs for intermittent claudication

Article Abstract:

Cardiovascular risk is reduced by supervised exercise and produces symptomatic improvement in patients with intermittent claudication. It was however concluded that the most important risk modifier is to stop smoking.

United States, Causes of, Drug therapy, Peripheral vascular diseases, Intermittent claudication

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