An outbreak of multidrug-resistant tuberculosis among hospitalized patients with the acquired immunodeficiency syndrome

Article Abstract:

AIDS patients with tuberculosis who contract the disease in the hospital may be more likely to likely to have a form of the disease that is resistant to treatment, than those who did not. Since 1990, several hospitals have reported AIDS patients who have developed multidrug-resistant tuberculosis. Eighteen AIDS patients with multidrug-resistant tuberculosis (case patients) were compared to 30 AIDS patients with tuberculosis susceptible to treatment with drugs. Fourteen case patients were hospitalized during the six months before diagnosis with tuberculosis, compared to 10 patients with drug-susceptible tuberculosis. Thirteen case patients were hospitalized on a ward with a patient with infectious drug-resistant tuberculosis, compared to two with drug-susceptible tuberculosis. Fifteen out of 16 case patients were infected with an identical form of Mycobacterium tuberculosis, the bacterium that causes tuberculosis. Only one of 16 rooms in which case patients were hospitalized had the recommended type of ventilation.

Risk factors, AIDS patients, Tuberculosis, Cross infection

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An epidemic of Malassezia pachydermatis in an intensive care nursery associated with colonization of health care workers' pet dogs

Article Abstract:

An outbreak of a fungal infection caused by the yeast organism Malassezia pachydermatis at the Dartmouth-Hitchcock Medical Center appears to have been transmitted by health care workers who got the infection from their pet dogs. Between Oct 17, 1993 and Jan 18, 1995, 15 infants in the neonatal intensive care unit became infected with the fungus and 9 others tested positive but had no active infection. An investigation revealed that one health care worker and 12 dogs owned by other health care workers tested positive also. In 9 infants, the one health care worker and three of the dogs, the fungus was identical.

Health aspects, Infants (Newborn), Dogs, Neonatal diseases, Mycoses

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