HMG-CoA Reductase Inhibitors and the Risk of Fractures

Article Abstract:

A group of drugs called statins appears to lower the risk of bone fractures. Statins are used to treat high cholesterol levels. In a study of 3,940 people who had a bone fracture and 23,379 who did not, the use of statins reduced the risk of bone fracture by 45%. Animal studies have shown that statins increase bone density.

Bones, Prevention, Fractures (Injuries), Fractures, Anticholesteremic agents

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Use of beta-blockers and risk of fractures

Article Abstract:

A study is conducted to determine whether the use of beta-blockers alone or in combination with thiazides is associated with a decreased risk of fracture in adults. Many elderly patients with hypertension who are at risk of developing osteoporisis may potentially benefit from combined therapy with beta-blockers and thiazides.

United States, Pharmaceutical Preparation Manufacturing, Pharmaceutical preparations, Beta Blockers, Care and treatment, Dosage and administration, Osteoporosis, Adrenergic beta blockers, Adrenergic beta-antagonists, Thiazides

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Antibiotics and Risk of Subsequent First-time Acute Myocardial Infarction

Article Abstract:

Bacterial infections may be a risk factor for heart attack. Researchers analyzed antibiotic use in the previous three years by 3,315 heart attack patients and 13,139 healthy people of similar age. Heart attack patients were about 30% less likely to have used tetracycline antibiotics and half as likely to have used quinolone antibiotics as the healthy volunteers. These antibiotics are effective against Chlamydia pneumoniae, which is additional evidence that this bacterium may be involved in heart disease. There were no differences between the two groups in the use of erythromycin, sulfonamides, penicillin, or cephalosporins.

Antibiotics, Risk factors, Heart attack

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