Antiretroviral treatment simplification with 3 NRTIs or 2 NRTIs plus Nevirapine in HIV-1-infected patients treated with successful first-line HAART
Article Abstract:
An antiretroviral treatment simplification with coformulated zidovudine/lamivudine/abacavir (group 1) is compared with coformulated zidovudine/lamivudine plus nevirapine (group 2) in HIV-infected patients to assess its virologic noninferiority. It is concluded that group 1 is not inferior to group 2 regarding virologic suppression <200 copies/mL and both strategies improve lipid profile.
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2005
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Lopinavir/Ritonavir plus nevirapine as a Nucleoside-sparing approach in antiretroviral-experienced patients (NEKA Study)
Article Abstract:
A study is made to compare the efficacy and safety of a nucleoside sparing approach with a conventional highly active antiretroviral therapy (HAART) regimen in antiretroviral-experienced patients with prolonged viral suppression. The result showed that all patients maintained viral suppression after 48 weeks and no subject discontinued therapy because of adverse events.
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2005
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Treatment interruptions guided by CD4 counts and viral load
Article Abstract:
The rationale for treatment discontinuation in patients with undetectable or detectable plasma viral load was discussed. Successful treatment interruption was found to be associated with age (<35 years), high CD4 nadir, high pre-highly active antiretroviral therapy (HAART) CD4, and low pre-HAART viral load.
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2006
User Contributions:
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