Association between multiple cardiovascular risk factors and atherosclerosis in children and young adults

Article Abstract:

Children and young adults with one or more risk factors for cardiovascular disease are more likely to have fatty streaks and plaques in their blood vessels that could lead to atherosclerosis. Researchers examined autopsy samples from the aorta and coronary arteries of 93 young people aged 2 to 39 years who died from different causes. Cardiovascular risk factors included obesity, smoking, high blood pressure, and elevated blood levels of cholesterol, triglycerides and other fats. The more risk factors the individual had, the greater the amount of fatty streaks and plaques in the aorta and coronary arteries.

Physiological aspects, Demographic aspects, Risk factors (Health), Atherosclerosis

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Longitudinal changes in cardiovascular risk from childhood to young adulthood in offspring of parents with coronary artery disease: the Bogalusa Heart Study

Article Abstract:

Children whose parents have coronary artery disease (CAD) may be at greater risk of developing cardiac risk factors as they grow older. In an 19-year study of 1,524 young people in Bogalusa, LA, those with a parent with CAD were more likely to be overweight and to develop early unhealthy changes in blood lipids and glucose. Overweight was apparent at 10-11 years of age. Parental CAD was associated with unhealthy cholesterol levels in white males and increased insulin levels in black males. Early screening for cardiovascular risk factors may be important in young people with a parental history of CAD.

Genetic aspects, Hyperlipidemia

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Childhood cardiovascular risk factors and carotid vascular changes in adulthood: the Bogalusa Heart Study

Article Abstract:

Children who are overweight and have high LDL cholesterol levels are more likely than other children to develop atherosclerosis as young adults, according to a study of 486 people 25 to 37 years old. All of them were part of the Bogalusa Heart Study, and had been examined by a doctor every three or four years since childhood. Ultrasound scans of their neck were done to detect the presence of atherosclerosis in the carotid arteries.

Children, Risk factors, Development and progression

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