Azithromycin for empirical treatment of the nongonococcal urethritis syndrome in men: a randomized double-blind study

Article Abstract:

A single dose of azithromycin appears to be as effective as standard seven-day doxycycline therapy in curing nongonococcal urethritis. Nongonococcal urethritis is a sexually transmitted urethral infection in men. Researchers administered oral antibiotics to 371 men with nongonococcal urethritis. Of these, 248 received a single, one gram dose of azithromycin and 123 received 200 milligrams of doxycycline per day for one week. The cumulative cure rate was 81% among azithromycin-treated patients and 77% in doxycycline-treated patients. In nongonococcal urethritis cases caused by the Chlamydia trachomatis bacterium, the overall microbiological cure rate was 83% in azithromycin-treated patients and 90% in doxycycline-treated patients. In nongonococcal urethritis cases cased by the Ureaplasma urealyticum bacterium, the overall microbiological cure rate was 45% in azithromycin-treated patients and 47% in doxycycline-treated patients.

Drug therapy, Azithromycin, Doxycycline, Urethritis, Nongonococcal, Nongonococcal urethritis

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Efficacy of Risk-Reduction Counseling to Prevent Human Immunodeficiency Virus and Sexually Transmitted Diseases

Article Abstract:

Brief, personalized counseling in sexually transmitted disease (STD) clinics can effectively increase condom use and decrease new STD infections. Researchers compared standard, safe sex training with personalized counseling and training for 5,758 heterosexual clients 14 years old or older. Brief individualized counseling, which included free condoms and a $15 payment, resulted in more clients reporting 100% condom usage than those who received generalized safe sex training. At six months, about 7% of counseled clients developed a new STD, compared to 10% of those who received standard safe sex instructions.

Prevention, Study and teaching, Condoms, Sexually transmitted disease prevention, Hygiene, Sexual, Sexual hygiene, Sex counseling

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Delayed presentation to clinics for sexually transmitted diseases by symptomatic patients: a potential contributor to continuing STD morbidity

Article Abstract:

Strategies that encourage patients to seek early treatment for suspected sexually transmitted diseases (STD) may better control these diseases. Questionnaires were completed by 1,621 symptomatic patients attending one of five STD clinics nationwide. Over one-third of the polled patients had waited a week or more to seek treatment. Nearly half of those patients that waited stated that they thought the conditions would go away. Similar rates were found for men and women. Men with gonorrhea were more likely to seek early treatment than those with genital warts or various infections of the urethra.

Care and treatment, Ambulatory care facilities, Beliefs, opinions and attitudes, Patients, Clinics

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