Calcium and vitamin D3 supplementation prevents bone loss in the spine secondary to low-dose corticosteroids in patients with rheumatoid arthritis: a randomized, double-blind, placebo-controlled trial
Article Abstract:
Vitamin D3 and calcium treatments appear to increase bone formation at some sites in patients with rheumatoid arthritis treated with steroids. Bone formation is measured by bone mineral density. For two years 96 patients with rheumatoid arthritis took one of four treatments including prednisone, vitamin D3, and calcium; prednisone and placebo; vitamin D3, calcium, and placebo; or placebo alone. Bone mineral densities in the upper leg and lower spine increased by 0.85% and 0.72% in patients taking prednisone, calcium, and vitamin D3. These measurements decreased or did not change in the other treatment groups.
Publication Name: Annals of Internal Medicine
Subject: Health
ISSN: 0003-4819
Year: 1996
User Contributions:
Comment about this article or add new information about this topic:
Gains in bone mineral density with resolution of vitamin D intoxication
Article Abstract:
Patients with unexplained bone loss may be ingesting excessive amounts of vitamin D. Vitamin D causes calcium to be released from bones. During a screening program for people with possible bone loss, researchers identified four people who had elevated blood levels of vitamin D and elevated urinary levels of calcium. The man and three women were all taking various vitamin and calcium supplements. When they stopped the supplements, their vitamin D levels dropped as did the excretion of calcium in the urine. Three years later, their spinal bone density had increased an average of 5%
Publication Name: Annals of Internal Medicine
Subject: Health
ISSN: 0003-4819
Year: 1997
User Contributions:
Comment about this article or add new information about this topic:
Bone loss in women with anorexia nervosa
Article Abstract:
Girls and women with anorexia nervosa are more likely than other girls to have weak bones that could fracture. In a study of 130 women with anorexia nervosa, about 90% had abnormally low bone density at one or more places in the skeleton.
Publication Name: Annals of Internal Medicine
Subject: Health
ISSN: 0003-4819
Year: 2000
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Intrathecal ziconotide in the treatment of refractory pain in patients with cancer or AIDS: a randomized controlled trial
- Abstracts: Accelerated bone loss in hypothyroid patients overtreated with L-thyroxine. Secondary osteoporosis: the potential relevance of leptin and low body weight
- Abstracts: Physicians and the pharmaceutical industry. An Association for Patient-Oriented Research. Young physician-scientists: internal medicine's challenge