Can nicotine treat sepsis?

Article Abstract:

Patients affected by sepsis often develop multiple organ failure, including shock, resulting from an overwhelming inflammatory response, despite treatment with appropriate drugs. Treatment with the acetylcholine receptor agonist, nicotine, modulates interactions between the nervous system and the immune system and reduces mortality in a mouse model of sepsis.

Drug therapy, Nicotine, Bacterial infections, Dosage and administration

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The curiosity of IL-15

Article Abstract:

Researchers have shown that the cytokine interleukin (IL)-15 acts intracellularly to reduce protease activity in mast cells and limits the protective response to sepsis. They have provided information about the complex series of events during sepsis and have shown that IL-15 has represented a target for clinical intervention.

Health aspects, Proteases, Mast cells, Interleukin-15, Clinical report

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Pulmonary barriers to pneumonia and sepsis

Article Abstract:

The conditions under which pneumonia progresses to sepsis and the effect of the lungs are examined in the presented article.

Risk factors, Development and progression, Pneumonia, Lung diseases, Bacterial pneumonia

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