Cerebellar growth in normal and growth-restricted fetuses of multiple gestations

Article Abstract:

The growth retarded fetus may preserve the growth of its brain, as noted by normal measurements of brain diameter in small-for-age fetuses. Researchers performed ultrasound examinations on the fetuses of pregnant women and compared brain diameter measurements of normal-for-gestational age fetuses with those of growth-restricted fetuses in twin and triplet pregnancies. The transverse cerebellar diameter measurement was found to be fairly constant among normal and growth-restricted fetuses, and correlated well with gestational age. Other body measurements of growth-restricted fetuses were smaller than normal, with most measurements below the tenth percentile. Early diagnosis of fetal growth retardation may allow intervention that can prevent fetal death.

Fetus, Growth, Fetal development, Cerebellum, Multiple birth

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Do low-risk pregnant women with antiphospholipid antibodies need to be treated?

Article Abstract:

Low-risk pregnant women who have antiphospholipid antibodies may not benefit from treatment with aspirin. Researchers identified 19 pregnant women with antiphospholipid antibody syndrome, a syndrome which can result in significant complications for both mother and fetus, but who did not exhibit symptoms of the syndrome and who had low rates of fetal compromise. Eleven women received treatment with low doses of aspirin while eight women received standard obstetric care. A low rate of fetal compromise was found in both groups, suggesting that aspirin treatment is not warranted for similar low-risk women.

Drug therapy, Antiphospholipid syndrome, Aspirin

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Dietary intake of myo-inositol and neural tube defects in offspring of diabetic rats

Article Abstract:

Supplementing the diets of diabetic pregnant women with myo-inositol may decrease by half the occurrence of birth defects among their infants. Myo-inositol is a fat that occurs in membranes, the integrity of which may be important in the developing embryo. Researchers studied the effects of induced diabetes and myo-inositol administration on 70 pregnant rats. Embryos of rats that received myo-inositol had half as many neural tube defects as embryos of rats not given myo-inositol, 9.5% versus 20.4%. High levels of maternal blood sugar, as occurs in diabetes, may cause birth defects.

Health aspects, Abnormalities, Prevention, Complications and side effects, Diabetes, Diabetes mellitus, Birth defects, Neural tube, Neural tube defects, Inositol

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