Characteristics of Trichomonas vaginalis isolates from women with and without colpitis macularis

Article Abstract:

Trichomoniasis is a common infection among sexually active women. It can be difficult to diagnose by a physical examination alone; isolation of the organism from tissue samples is needed to confirm its presence. Previous studies of women with genital infections indicated that colpitis macularis ('strawberry cervix') was the best predictive clinical sign for presence of trichomoniasis. In the same study, though, only 50 percent of the women with trichomoniasis had colpitis macularis. These studies were extended to determine if colpitis macularis correlated with some characteristic of trichomoniasis infection, such as type of strain, amount of organism, virulence, or presence of purulent vaginal discharge. Among 12 infected women who had no other genital infections, there was no relationship between presence of colpitis macularis and amount of organism present or virulence as measured by three different techniques. Purulent discharge, which was previously found to be a somewhat predictive sign of trichomoniasis, was confirmed to be associated with presence of colpitis macularis. As colpitis macularis and purulent discharge did not correlate with any of the postulated characteristics, it is suggested that these signs may instead reflect the stage of infection and immune reaction, or they may depend on other organisms to reach full development. Alternatively, the techniques used to measure virulence may not be relevant to the organism's function. Further studies of the biology of trichomoniasis and interaction with human tissue are needed to before the disease can be better diagnosed and understood. (Consumer Summary produced by Reliance Medical Information, Inc.)

Sexually transmitted diseases, Identification and classification, Trichomonas vaginalis, Trichomonas

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Clinical manifestations of trichomoniasis in men

Article Abstract:

Men at risk for contracting sexually transmitted diseases often have symptoms of non-specific urethritis related to trichomoniasis infection. Of 147 heterosexual men whose partners were infected with Trichomoniasis vaginalis, 22% were also infected. Of 300 heterosexual men chosen randomly from visits to the same clinic, only 6% were infected with T. vaginalis. Signs of infection were evident in more than half of the men with trichomoniasis. Urethral discharge was the most common symptom of infection. Trichomoniasis infection was associated with mild to moderate levels of non-specific urethritis. Male partners of women with trichomoniasis should be screened and treated if necessary. Men with mild symptoms of urethritis should also be screened.

Health aspects, Demographic aspects, Men, Men's health, Urethritis, Nongonococcal, Nongonococcal urethritis

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The role of spermatozoa in the pathogenesis of Chlamydia trachomatis salpingitis in a primate model

Article Abstract:

Spermatozoa may not play a role in the development of Chlamydial salpingitis. Chlamydial salpingitis is inflammation of the fallopian tubes caused by infection with Chlamydia trachomatis, a pathogenic microorganism that is sexually transmitted. Among eight female monkeys whose cervix was infected with C. trachomatis, five had sexual intercourse with male monkeys and three did not. Of the 16 samples taken of spermatozoa taken from the monkeys, only one contained C. trachomatis. C. trachomatis was not cultured from the fallopian tubes of any of the monkeys who mated. It was cultured from the fallopian tubes of only one monkey who did not mate. None of the monkeys developed salpingitis without direct infection of the fallopian tubes.

Causes of, Development and progression, Chlamydia infections, Spermatozoa, Sperm, Salpingitis

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