Clinical use of first-trimester aneuploidy screening in a United States population can replicate data from clinical trials

Article Abstract:

A study is conducted to evaluate the performance of maternal age, fetal nuchal translucency measurements, pregnancy-associated plasma protein A, and free beta-human chorionic gonadotrophin used in aneuploidy screening in a single institution outside of a clinical trial. The findings suggest that non-investigational use of first-trimester aneuploidy screening for trisomy 21 and trisomy 18 can replicate results form investigational trials.

United States, Science & research, Research, Down syndrome, Aneuploidy

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Factors associated with fetal demise in fetal echogenic bowel

Article Abstract:

Increased blood levels of alpha-fetoprotein in pregnant women is a strong risk factor for fetal death in fetuses who have echogenic bowel. Echogenic bowel is an abnormality seen on ultrasound scans of the intestines.

Health aspects, Abnormalities, Causes of, Fetal death, Alpha fetoproteins

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The clinical significance of fetal echnogenic bowel

Article Abstract:

Echogenic bowel in a fetus may be a sign of cystic fibrosis or a chromosome abnormality, according to a study of 171 pregnant women. Echogenic bowel is an abnormality seen on an ultrasound scan of the intestines.

Evaluation, Cystic fibrosis

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