Coffee, caffeine and cardiovascular disease in men
Article Abstract:
Several papers over the past decade have linked coffee drinking with an increased incidence of heart attack. However, this putative association has not been proven, in part, because most studies have not included a sufficiently large population. The present prospective study examined the relationship between coffee drinking and heart attack, coronary artery bypass surgery, and stroke in a large population. The study group of 51,529 professional men (dentists, pharmacists, podiatrists, veterinarians, osteopaths, and physicians) was surveyed, and pertinent medical and family histories, which included smoking and heart disease, were abstracted. Individuals with a prior history of heart trouble, coronary artery surgery, or stroke were eliminated. The remaining 45,589 men were included in a two-year follow-up study. During this period, 221 participants suffered a non-fatal heart attack, 136 underwent coronary artery surgery, and 54 experienced a stroke (a cerebrovascular accident). In this group of men, the relative risk of drinking regular coffee failed to reveal any association with heart disease or stroke. There was a slight, but statistically significant increase in cerebrovascular disease associated with increased consumption of decaffeinated coffee. This study, which included a large population, failed to confirm any association between caffeine consumption from all sources and the incidence of heart attack, coronary artery surgery, and stroke. (Consumer Summary produced by Reliance Medical Information, Inc.)
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1990
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Vitamin E consumption and the risk of coronary heart disease in men
Article Abstract:
Consumption of vitamin E supplements may reduce the risk of coronary heart disease in middle-aged men. Vitamin E is an antioxidant that may also help protect against the development of atherosclerosis. Among 39,910 male health professionals between 40 and 75 years old who were followed over a four-year period, 667 coronary events occurred. These included 360 bypass graft operations or angioplasties, 201 non-fatal heart attacks and 106 fatal heart attacks. Men who consumed more than 60 IU of vitamin E per day had a lower risk of coronary heart disease than those who consumed less than 7.5 IU per day. Dietary carotene, another antioxidant, was associated with a lower risk of coronary heart disease in men who were current smokers. This association was not found in men who had never smoked.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1993
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Recreational physical activity and the risk of cholecystectomy in women
Article Abstract:
Physical inactivity may increase a woman's risk of developing gallstones. Among 60,290 women participating in the Nurses' Health Study, those who were the most sedentary had twice the risk of developing gallstones as those who were the most active. This was true even after adjusting the data for body weight and weight change. Gallstones are the most common cause of hospitalization and the most costly.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1999
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